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Objective: Citrullination has become a hot topic within recent years due to its involvement in diseases such as rheumatoid arthritis (RA), multiple sclerosis and fibrosis. Citrullinations are the conversion of arginine to citrulline by peptidylarginine deiminase (PAD) enzymes, which affect protein p...
December 18, 2014
Journal:
Autoimmunity
Author:
Gudmann NS, Brandt-Hansen NU, Bay-Jensen AC, Karsdal MA, Siebuhr AS
Background: Osteoarthritis (OA) is the most common degenerative joint disease, of which the pathogenesis is inadequately understood. Hypertrophy-like changes have been observed as part of the progression of OA. The aim of the study was to develop and characterize a novel biomarker of chondrocytes hy...
September 22, 2014
Journal:
BMC Musculoskelet Disord
Author:
He Y, Siebuhr AS, Brandt-Hansen NU, Wang J, Su D, Zheng Q, Simonsen O, Petersen KK, Arendt-Nielsen L, Hoeck HC, Karsdal MA, Bay-Jensen AC, Eskehave TN
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