Find an abstract and a link to most of the publications produced by Nordic Bioscience
Osteoarthritis, rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis, all have one clear common denominator; an altered turnover of bone. However, this may be more complex than a simple change in bone matrix and mineral turnover. While these diseases share a common tissue axis, thei...
December 21, 2020
Journal:
BMC Musculoskelet Disord.
Author:
Thudium CS, Nielsen SH, Sardar S, Mobasheri A, van Spil WE, Lories R, Henriksen K, Bay-Jensen AC, Karsdal MA.
Background: Matrix metalloproteinase-3 (MMP-3) plays an important role in the pathology of rheumatoid arthritis (RA) and ankylosing spondylitis (AS). Measurement of active MMP-3 in clinical samples could provide information about progression of rheumatoid diseases, and potentially response to treatm...
March 19, 2014
Journal:
BMC Musculoskelet Disord.
Author:
Sun S, Bay-Jensen AC", "Karsdal MA", "Siebuhr AS", "Zheng Q", "Maksymowych WP", "Christiansen TG", "Henriksen K"
Background: Bone resorption is initiated by osteoclastic acidification of the resorption lacunae. This process is mediated by secretion of protons through the V-ATPase and chloride through the chloride antiporter ClC-7. To shed light on the intracellular signalling controlling extracellular acidific...
October 26, 2010
Journal:
BMC Musculoskelet Disord.
Author:
Sørensen MG, Karsdal MA, Dziegiel MH, Boutin JA, Nosjean O, Henriksen K
Background: Calcitonin has been demonstrated to have chondroprotective effects under pre-clinical settings. It is debated whether this effect is mediated through subchondral-bone, directly on cartilage or both in combination. We investigated possible direct effects of salmon calcitonin on proteoglyc...
April 5, 2010
Journal:
BMC Musculoskelet Disord.
Author:
Sondergaard BC, Madsen SH, Segovia-Silvestre T, Paulsen SJ, Christiansen T, Pedersen C, Bay-Jensen AC, Karsdal MA
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