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KBP-042 is a synthetic peptide dual amylin- and calcitonin-receptor agonist (DACRA) developed to treat type 2 diabetes by inducing a significant weight loss while improving glucose homeostasis. In this study the aim was to compare two different formulations: An oral formulation (1mg/kg) to subcutane...
September 5, 2015
Journal:
Eur J Pharmacol
Author:
Hjuler ST, Andreassen KV, Gydesen S, Karsdal MA, Henriksen K
We previously reported that oral delivery of salmon calcitonin (sCT) improved energy and glucose homeostasis and attenuated diabetic progression in animal models of diet-induced obesity (DIO) and type 2 diabetes, although the glucoregulatory mode of action was not fully elucidated. In the present st...
May 22, 2014
Journal:
Eur J Pharmacol
Author:
Feigh M, Andreassen KV, Gydesen S, Ottosen I, Henriksen JE, Beck-Nielsen H, Christiansen H, Karsdal MA, Henriksen K
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