Month: March 2022

Osteoarthritis Biomarkers – Serum Quantification of Aggrecanase-Generated ARGS Fragments

Posted on by Claire Hornung

Serum Quantification of Aggrecanase-Generated ARGS Fragments

Osteoarthritis is a serious disease. It affects more than 300 million people across the world. It’s a leading cause of disability among older adults. Therefore, it has a considerable impact on an individual’s quality of life and a huge economic burden on society.

We redeveloped a highly sensitive and robust sandwich immunoassay, huARGS, for detecting ARGS fragments generated by up-regulated proteases, ADAMTS-4/-5, during osteoarthritis.

Watch more videos about how our biomarker can increase clinical trial success rates on our YouTube channel!

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    Joint Tissue Remodeling: Joint and Connective Tissue Disorder Profiling

    Posted on by Claire Hornung

    Joint and Connective Tissue Disorder Profiling

    According to conservative estimates, nearly 26% of all adults in the United States are expected to have at least one form of arthritis by 2040. The tissues of the joints are composed primarily of collagens.

    Collagens are remodeled as part of the normal homeostasis of the joint – that is, collagens are broken down and rebuilt as part of the repair and maintenance mechanisms of the tissue.

    When this balance is disrupted, there is a net breakdown of joint tissue. Learn more how Protein Fingerprint biomarkers can quantify this tissue turnover directly in a serum sample.

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    Are you interested in exploring collaboration possibilities?
Enter your information in the form and a representative will contact you shortly.
    +45 4452 5252 Contact us via email!