Publication Year: 2026

Cytokine profiling of molecular endotypes of knee osteoarthritis: insights from the IMI-APPROACH cohort.

January 27, 2026

Arthritis Res Ther

Abstract BACKGROUND Molecular endotypes that decipher the heterogeneity of osteoarthritis (OA) have been described. This exploratory study aimed to further the molecular understanding of three previously identified biomarker-based endotypes of knee OA through cytokine profiling. METHODS Fifteen pro- and anti-inflammatory cytokines were measured in serum at the six-, 12-, and 24-month follow-up visits of 277 […]

 Read publication

Binge drinking acutely induces hepatic steatosis which is readily reversible: A real-world observational study in healthy adults.

January 1, 2026

JHEP Rep

Abstract BACKGROUND & AIMS Binge drinking is a common pattern of alcohol intake often considered particularly harmful. However, its immediate effects on the development of hepatic steatosis and early alcohol-related liver injury are not well established. This study aimed to investigate the acute effects of binge drinking on the liver and its reversibility in healthy […]

 Read publication