A matrix metalloproteinase-generated fragment of type III collagen, reflecting extracellular matrix remodeling and enabling assessment of fibrotic activity.
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C4G
A granzyme B-generated neo-epitope fragment of type IV collagen, enabling non-invasive assessment of T-cell infiltration and basement membrane remodeling in tumor and inflammatory microenvironments.
C4M
A neo-epitope fragment of type IV collagen generated by matrix metalloproteinase activity, enabling non-invasive assessment of basement membrane degradation and extracellular matrix remodeling in chronic inflammatory and fibrotic diseases.
C6A6
A neo-epitope fragment of the α6 chain of type VI collagen, enabling non-invasive monitoring of dermal extracellular matrix remodeling and fibroblast activation in inflammatory skin disorders.
C6M
A fragment of type VIa1 collagen released by MMP-2. Special beaded filament collagen measuring interstitial ECM destruction. A neo-epitope fragment of type VI collagen generated by matrix metalloproteinase activity, enabling non-invasive assessment of interstitial extracellular matrix remodeling in fibrotic and oncological conditions.
C7M
A neo-epitope fragment of type VII collagen generated by matrix metalloproteinase activity, enabling non-invasive monitoring of dermal-epidermal junction integrity and tissue remodeling in fibrotic and inflammatory skin disorders.
CPa9-HNE (nordicCPa9™, serum calprotectin)
A fragment of S100A9 (calprotectin) released by neutrophil elastase measured in blood, enabling precise assessment of active neutrophil-driven inflammation in systemic and tissue-specific conditions.
EL-CG
A neo-epitope fragment of elastin generated by cathepsin G activity, enabling non-invasive monitoring of elastin degradation and extracellular matrix remodeling in dermatology and chronic respiratory diseases.
ELA-HNE
A neo-epitope fragment of elastin generated by neutrophil elastase activity, enabling non-invasive monitoring of extracellular matrix degradation and inflammation in chronic respiratory and gastrointestinal diseases.
Elecsys PRO-C3® (automated)
A neo-epitope fragment of type III collagen released during extracellular matrix remodeling, enabling non-invasive quantification of active fibrogenesis and dynamic assessment of fibrosis progression and treatment response. Elecsys automated version: An in vitro diagnostic (IVD)-labelled assay developed in collaboration with Roche Diagnostics. It is intended for clinical use under regulated conditions.