Biomarkers

A fragment of the C-terminal propeptide of type V fibrillar collagen, enabling non-invasive monitoring of extracellular matrix, myfibroblast and cancer-associated fibroblast (CAFs) formation, indicating fibrotic activity in hepatic and oncological conditions.

A citrullinated and matrix metalloproteinase-degraded fragment of vimentin, enabling non-invasive monitoring of macrophage-driven inflammation and tissue remodeling across autoimmune and fibrotic diseases.

A neo-epitope fragment of type I collagen generated by MMP activity, quantifying pathological soft tissue destruction and extracellular matrix turnover.

A fragment of the alpha-1 chain of type III collagen generated by human neutrophil elastase (HNE), enabling non-invasive detection of early mucosal inflammation and extracellular matrix remodeling in gastrointestinal disorders.

A neo-epitope fragment of type III collagen generated by fibroblast activation protein (FAP) activity, enabling non-invasive assessment of fibroblast-driven extracellular matrix remodeling in fibrotic and oncologic conditions.

A neo-epitope fragment of the α3 chain of type IV collagen generated by neutrophil elastase activity, enabling non-invasive detection of early mucosal injury and basement membrane remodeling in inflammatory bowel disease.

A fragment of the alpha-4 chain of type IV collagen generated by human neutrophil elastase (HNE). Networking forming collagen measuring neutrophil activity.

A fragment of type VIa1 collagen released by MMP-2. Special beaded filament collagen measuring interstitial ECM destruction. A neo-epitope fragment of type VI collagen generated by matrix metalloproteinase activity, enabling non-invasive assessment of interstitial extracellular matrix remodeling in fibrotic and oncological conditions.

A neo-epitope fragment of the α3 chain of type VI collagen generated by matrix metalloproteinase activity, enabling non-invasive assessment of intestinal extracellular matrix remodeling and disease activity in inflammatory bowel conditions.

A neo-epitope fragment of type VII collagen generated by matrix metalloproteinase activity, enabling non-invasive monitoring of dermal-epidermal junction integrity and tissue remodeling in fibrotic and inflammatory skin disorders.