Biomarkers

A neo-epitope fragment of elastin generated by cathepsin G activity, enabling non-invasive monitoring of elastin degradation and extracellular matrix remodeling in dermatology and chronic respiratory diseases.

A neo-epitope fragment of elastin generated by neutrophil elastase activity, enabling non-invasive monitoring of extracellular matrix degradation and inflammation in chronic respiratory and gastrointestinal diseases.

A neo-epitope fragment of elastin generated by neutrophil elastase activity, enabling non-invasive monitoring of extracellular matrix degradation and inflammation in chronic respiratory and gastrointestinal diseases.

A neo-epitope fragment of type III collagen released during extracellular matrix remodeling, enabling non-invasive quantification of active fibrogenesis and dynamic assessment of fibrosis progression and treatment response. Elecsys automated version: An in vitro diagnostic (IVD)-labelled assay developed in collaboration with Roche Diagnostics. It is intended for clinical use under regulated conditions.

A fragment of elastin cleaved by proteinase 3, enabling non-invasive monitoring of neutrophil-driven extracellular matrix degradation and inflammation in chronic diseases.

N-terminal of EMID1 after cleavage of signal peptide

A bioactive fragment of type VI collagen known as Endotrophin quantifying the intact 77-amino-acid Endotrophin signaling hormone, enabling non-invasive quantification of fibro-inflammatory signaling and risk stratification in chronic disease and oncology.

A fragment of fibronectin generated by matrix metalloproteinase activity, enabling non-invasive monitoring of extracellular matrix remodeling and fibrotic activity in chronic tissue disorders.

A fragment of glial fibrillary acidic protein cleaved by caspase-6, enabling non-invasive monitoring of astrocytic activation and central nervous system injury.

C-terminal end of heat shock protein 47