Abstract Given the complexity of the biosynthetic machinery and the delicate chemical composition of proteins, it is remarkable that cells manage to produce and maintain normally functioning proteins under most conditions. However, it is now well known that proteins are susceptible to various non-enzymatic covalent modifications (NECM) under physiological conditions. Such modifications can be of […]
Non-enzymatic covalent modifications of proteins: mechanisms, physiological consequences and clinical applications.
January 1, 2002
Matrix Biol
