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Correction: Predictive value of BMD for hip and other fractures: a meta-analysis to update FRAX.
April 1, 2026
Osteoporos Int
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Prognostic Performance of Phosphatidylethanol With Noninvasive Liver Fibrosis Tests in Alcohol-Related Liver Disease.
April 1, 2026
Gastroenterology
Abstract BACKGROUND & AIMS Alcohol is a key driver of liver-related mortality, and phosphatidylethanol (PEth) is a direct biomarker of alcohol intake. We investigated the prognostic performance of PEth with noninvasive liver fibrosis tests (NITs) for predicting hepatic decompensation in an alcohol-related liver disease (ALD) at-risk population. METHODS Prospective cohort study with 411 at risk […]
Collagen protein supplementation does not modulate biomarkers of bone metabolism following total hip arthroplasty: A randomized, double-blind, placebo-controlled trial.
March 27, 2026
Clin Nutr ESPEN
Abstract BACKGROUND & AIMS Healing after total hip arthroplasty (THA) involves remodelling of collagenous tissues, such as bone. While collagen protein supplementation has been suggested to modulate bone metabolism, the effects following THA are yet to be investigated. Therefore, we aimed to characterize changes in biomarkers of bone metabolism following THA and to assess the […]
Correction: A meta-analysis of previous falls and subsequent fracture risk in cohort studies.
March 24, 2026
Osteoporos Int
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Characterization of a novel assay for full-length endotrophin in heart failure with preserved ejection fraction.
March 18, 2026
Sci Rep
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Predictive value of BMD for hip and other fractures: a meta-analysis to update FRAX.
March 12, 2026
Osteoporos Int
Abstract UNLABELLED The relationship between bone mineral density (BMD) at the femoral neck and fracture risk was determined in a meta-analysis of primary data of 307205 men and women from 53 cohort studies. Low BMD was an important predictor of fracture risk, particularly for hip fracture. INTRODUCTION This study aimed to quantify the relationship between […]
Collagen type I degradation peptide as a predictive biomarker for mortality in ST-elevated myocardial infarction.
March 4, 2026
Clin Res Cardiol
Abstract BACKGROUND AND AIMS Tissue remodelling and extracellular matrix (ECM) changes are primary consequences of ST-elevated myocardial infarction (STEMI), leading to an increased risk of developing heart failure and mortality. Collagen type I is the top constituent of the cardiac ECM and is rapidly degraded at sites of tissue injury occurring in STEMI. We aimed […]
A meta-analysis of smoking and fracture risk to update the FRAX® tool.
March 4, 2026
Osteoporos Int
Abstract UNLABELLED In this meta-analysis of international cohorts, current smoking is confirmed as a significant BMD-independent predictor of future fracture with a stronger relationship in men than in women. A causative and reversible effect of smoking on fracture risk is suggested by past smoking having a significantly lower risk than current smoking. PURPOSE In this […]
Fibrosis activity vs. disease stage: Complementary and independent predictors of outcomes in alcohol-related liver disease.
March 1, 2026
JHEP Rep
Abstract BACKGROUND & AIMS Excessive alcohol consumption accelerates fibrosis progression in steatotic liver disease. Disease activity can be described by fibrogenic activity, of which collagen formation is a central process. Type III collagen formation (PRO-C3) is a biomarker of fibrosis activity. We aimed to evaluate whether PRO-C3 predicts clinical outcomes in alcohol-related liver disease (ALD) […]
Biomarkers of Extracellular Matrix Remodelling Are Linked to Severity and Outcome of Advanced Chronic Liver Disease.
March 1, 2026
Aliment Pharmacol Ther
Abstract BACKGROUND Extracellular matrix (ECM) remodelling in advanced chronic liver disease (ACLD) is characterised by hepatic fibrosis and (sinusoidal) basement membrane development contributing to portal hypertension (PH) and clinical complications. METHODS Patients with stable ACLD (n = 232) undergoing hepatic venous pressure gradient (HVPG) measurement were included. Blood biomarkers reflecting fibrosis formation (PRO-C3, PRO-C6, PRO-C4 and PRO-C18L) […]
