Biomarkers

A fragment of the LG3 domain of perlecan cleaved by BMP-1, enabling non-invasive monitoring of basement membrane remodeling and fibrotic activity in chronic kidney diseases. In heparin plasma and urine only.

A fragment of type IV collagen α3 chain generated by matrix metalloproteinase activity, enabling non-invasive monitoring of basement membrane remodeling and angiogenic activity in pathological conditions.