A neo-epitope fragment of type III collagen generated by fibroblast activation protein (FAP) activity, enabling non-invasive assessment of fibroblast-driven extracellular matrix remodeling in fibrotic and oncologic conditions.
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CAN (Canstatin)
Canstatin, released NC1 domain of type IV collagen a2 chain, enabling non-invasive monitoring of angiogenesis and extracellular matrix remodeling in pathological conditions such as cancer and fibrotic diseases.
Elecsys PRO-C3® (automated)
A neo-epitope fragment of type III collagen released during extracellular matrix remodeling, enabling non-invasive quantification of active fibrogenesis and dynamic assessment of fibrosis progression and treatment response. Elecsys automated version: An in vitro diagnostic (IVD)-labelled assay developed in collaboration with Roche Diagnostics. It is intended for clinical use under regulated conditions.
PRO-C8
A fragment of the NC1 domain of type VIII collagen, enabling non-invasive monitoring of epithelial basement membrane remodeling and tumor-associated fibrosis in solid tumors.
TUM
A fragment of type IV collagen α3 chain generated by matrix metalloproteinase activity, enabling non-invasive monitoring of basement membrane remodeling and angiogenic activity in pathological conditions.
