Biomarkers

A neo-epitope fragment of type III collagen released during extracellular matrix remodeling, enabling non-invasive quantification of active fibrogenesis and dynamic assessment of fibrosis progression and treatment response. Manual ELISA kit version: The kit is FOR RESEARCH USE ONLY (RUO) and can only be used in NON-CLINICAL settings. It can not be used IN DIAGNOSTIC PROCEDURES.

A fragment of the 7S domain of type IV collagen, enabling non-invasive monitoring of basement membrane formation and extracellular matrix remodeling in fibrotic diseases.

A fragment of the NC1 domain of type X collagen, enabling non-invasive monitoring of chondrocyte hypertrophy and cartilage matrix remodeling in osteoarthritis and inflammatory joint diseases.

A fragment of the N-terminal propeptide of type XI collagen, enabling non-invasive monitoring of cancer associated fibroblast-driven (CAF) extracellular matrix formation and tumor-associated fibrosis in oncology and fibrotic disorders.

A fragment of the C-terminal domain of type XII collagen, enabling non-invasive monitoring of cancer-associated fibroblast (CAFs) activity and extracellular matrix remodeling in solid tumors.

A fragment of the C-terminal domain of type XVI FACIT collagen, enabling non-invasive monitoring of extracellular matrix remodeling and fibrostenotic activity in gastrointestinal disorders such as colorectal cancer and Crohn's disease.

A fragment of the ectodomain of type XVII collagen, enabling non-invasive monitoring of epithelial damage and basement membrane remodeling in skin and gastrointestinal disorders.

A fragment of the C-terminal domain of type XIX collagen, enabling non-invasive monitoring of basement membrane remodeling and extracellular matrix dynamics in oncology research.

A fragment of the N-terminal propeptide of type IIB fibrillar collagen, enabling non-invasive monitoring of cartilage formation and chondrocyte anabolic activity in joint diseases such as osteoarthritis.

A fragment of the C-terminal domain of type XX collagen, enabling non-invasive monitoring of extracellular matrix remodeling and tumor-associated fibrosis across multiple solid tumor types.