Biomarkers

A fragment of α-synuclein cleaved by Calpain-1, enabling non-invasive monitoring of neurodegenerative protein aggregation and neuronal injury.

Human ADAMTS4 (ADAM with Thrombospondin Type 1 Motif 4)

Human ADAMTS5(A Disintegrin And Metalloproteinase With Thrombospondin 5)

A fragment of aggrecan from IGD1-2 released by ADAMTS-4/5, enabling non-invasive assessment of cartilage degradation and turnover in joint diseases.

A neo-epitope fragment of biglycan generated by MMP-9 and MMP-12 activity, reflecting pericellular matrix degradation and extracellular matrix remodeling.

A fragment of BIGH3 released by MMP-9

A neo-epitope fragment of type I collagen generated by MMP activity, quantifying pathological soft tissue destruction and extracellular matrix turnover.

A matrix metalloproteinase-generated neo-epitope fragment of type I collagen, enabling non-invasive assessment of extracellular matrix degradation and mortality risk in cardiovascular disease.

A neo-epitope fragment of type II collagen generated by matrix metalloproteinase activity, enabling direct assessment of cartilage degradation and turnover.