EL-CG

A neo-epitope fragment of elastin generated by cathepsin G activity, enabling non-invasive monitoring of elastin degradation and extracellular matrix remodeling in dermatology and chronic respiratory diseases.

Key features and values
  • Quantifies elastin fragments specifically generated by cathepsin G activity.
  • Reflects elastin degradation associated with extracellular matrix remodeling.
  • Provides a non-invasive measure of tissue remodeling dynamics.
  • Supports monitoring of disease progression and response to therapies targeting extracellular matrix turnover.
  • Applicable in research on chronic respiratory diseases and conditions characterized by abnormal elastin degradation.
  • Facilitates evaluation of interventions aimed at modulating extracellular matrix integrity.
  • Complements other biomarkers for a comprehensive assessment of extracellular matrix dynamics.
Description

The EL-CG biomarker assay measures specific neo-epitope fragments of elastin generated by cathepsin G activity, serving as an indicator of elastin degradation and extracellular matrix remodeling. This non-invasive assay provides insights into tissue remodeling dynamics in dermatology and chronic respiratory diseases. By quantifying elastin fragments produced by cathepsin G, the EL-CG assay aids in monitoring disease progression, evaluating treatment efficacy, and understanding the underlying mechanisms of diseases characterized by abnormal elastin degradation. It serves as a valuable tool in research settings for assessing the dynamics of extracellular matrix integrity.

Nordic Bioscience’s assays and services are research use only products and services and do not qualify for medical or diagnostic purposes.

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