Are you interested in exploring collaboration possibilities?
Enter your information in the form and a representative will contact you shortly.
NordicEndotrophin™ Is Prognostic of Outcome in Heart Failure Patients
March 29, 2025
Endotrophin, quantified by a novel biomarker, is prognostic of outcome in heart failure patients
Introduction
NordicEndotrophin™ is a type VI collagen-derived matrikine associated to mortality risk in heart failure. It can be quantified by nordicPRO-C6™, which targets the C-terminal of type VI collagen α3 chain. In this study, we evaluated the prognostic performance of a novel biomarker called full-length nordicEndotrophin™, specifically designed to target the 77aa molecule at both peptide termini. We investigated the performance of the novel assay in relation to NT-proBNP and nordicPRO-C6™.
Poster
Conclusion
This study presents the novel biomarker of full-length nordicEndotrophin™ demonstrating comparable performance to NT-proBNP and nordicPRO-C6™ in predicting mortality risk in HF patients. The biomarker’s prognostic value remains robust even after adjusting for relevant risk factors.
