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Skeletal muscle proteomics links mitochondrial abundance with peak fat oxidation in physically active young males.

July 1, 2026

J Physiol

Abstract The interindividual variability in peak fat oxidation (PFO) and the intensity at which this occurs (Fat) has been attributed to physiological factors, diet and physical activity; however, few studies have examined the contribution of skeletal muscle characteristics. The present study examined the relationship between PFO, Fat and the skeletal muscle proteome in young, physically […]

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Divergent Changes in Peak Fat Oxidation and Fat(max) Following 3-Day Dietary Interventions Are Related to Muscle Glycogen Availability in Men.

September 1, 2025

Scand J Med Sci Sports

Abstract Dietary intake has an important influence on rates of fuel use during exercise, but the extent to which short-term diet changes affect peak fat oxidation (PFO) and the intensity at which this occurs (Fat) is unknown. This study examined the impact of diet-induced changes in substrate availability on PFO and Fat and the expression […]

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Measurement of a MMP-2 degraded Titin fragment in serum reflects changes in muscle turnover induced by atrophy.

October 1, 2014

Exp Gerontol

Abstract PURPOSE In this study we sought to determine whether a Titin peptide fragment can serve as a clinical biomarker for changes in muscle mass. METHODS Mass spectrometry was used to identify Titin fragment in urine. An antibody against this Titin sequence was raised and used to develop a competitive ELISA assay for measurement in […]

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