ELP-3
A fragment of elastin cleaved by proteinase 3, enabling non-invasive monitoring of neutrophil-driven extracellular matrix degradation and inflammation in chronic diseases.
Key features and values
- Detects elastin fragments generated by proteinase 3 activity.
- Reflects neutrophil activation and degranulation processes.
- Indicates extracellular matrix degradation associated with inflammatory conditions.
- Applicable in research on diseases such as inflammatory bowel disease and respiratory disorders.
- Facilitates non-invasive assessment of tissue remodeling dynamics.
- Complements other biomarkers for a comprehensive evaluation of inflammatory tissue damage.
- Supports monitoring of disease progression and therapeutic response in chronic inflammatory diseases.
Description
The ELP-3 biomarker assay quantifies specific elastin fragments resulting from proteinase 3-mediated cleavage, serving as an indicator of neutrophil activity and extracellular matrix degradation. This non-invasive assay provides insights into tissue remodeling processes associated with chronic inflammatory conditions, including inflammatory bowel disease and respiratory disorders. By measuring elastin degradation products, the ELP-3 assay aids in monitoring disease progression, evaluating treatment efficacy, and understanding the underlying mechanisms of tissue inflammation and damage. It serves as a valuable tool in research settings for assessing the dynamics of extracellular matrix turnover and neutrophil-driven tissue remodeling.
Nordic Bioscience’s assays and services are research use only products and services and do not qualify for medical or diagnostic purposes.
