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Madrigal met both primary endpoints in the Phase 3 MAESTRO-NASH clinical trial of Resmetirom

We would like to congratulate Madrigal Pharmaceuticals for taking a major step toward improving the lives of patients with NASH.

Madrigal met both primary endpoints (NASH resolution and fibrosis stage improvement) in the Phase 3 MAESTRO-NASH clinical trial of Resmetirom for the treatment of NASH and liver fibrosis. This is a great testament to the hard work of the Madrigal team.

In a previous Phase 2 NASH clinical trial, Madrigal Pharmaceuticals showed that Resmetirom treatment significantly reduced levels of PRO-C3, suggesting that Resmetirom reduces the formation of collagen type III.

These findings are consistent with the current results of the MAESTRO-NASH clinical trial, which showed that treatment with Resmetirom leads to both NASH resolution and improvement in liver fibrosis.

Nordic Bioscience is pleased to have also supported the MAESTRO-NASH clinical trial with our biomarker for collagen type III formation (PRO-C3) and is eager to see the results!


Madrigal Press Release

Publication

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