Cancer can be described as a condition associated with fibrosis, also called tumor fibrosis. This fibrotic reaction occurring in the tumor's microenvironment is referred to as desmoplasia. It is marked by an excessive turnover and transformation of the extracellular matrix (ECM). Within fibrous tumors, there is an augmented production and crosslinking of collagen, along with changes in collagen matrix degradation, leading to the disruption of tissue organization and cell behavior. This, in turn, results in the release of growth factors and the creation of hidden signaling-active sites on collagen.

Speaker line-up and talking points:

  • Dr. Raghu Kalluri (Professor and Chairman, Department of Cancer Biology, University of Texas MD Anderson Cancer Center), is an expert in the cellular microenvironment and will discuss, among others, the unique and unexpected role of collagens in cancer.
  • Dr. Saurabh Gupta (Senior Director, Clinical Biomarkers Oncology, Precision Medicine), Bristol-Myers Squibb, is a clinical drug development and biomarker research expert and will provide valuable insights into the underlying mechanisms of tumor fibrosis and the association with clinical outcomes.
  • Dr. Nicholas Willumsen (Director, Oncology, Nordic Bioscience), will focus on the development and validation of blood-based biomarkers to quantify tumor fibrosis in serum from cancer patients and discuss how this may inform cancer-associated fibroblast (CAF) activity and subtyping.


Join us for a webinar on tumor fibrosis, where we will explore the latest advancements in cancer research with leading experts in the field. This webinar will provide a unique opportunity to hear from experts in the field and gain valuable insights into the latest advancements in tumor fibrosis research.

Join us to learn about cutting-edge approaches to developing new therapeutic targets, and the use of biomarkers for patient stratification and evaluating treatment efficacy.


The ECM Pharmacology Symposium Series is a close ongoing collaboration with The Extracellular Matrix Pharmacology Congress.

Please don't hesitate to contact us if you have any questions or other inquiries.