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INTRODUCTION: At present, no disease-modifying osteoarthritis drugs (DMOADS) are approved by the FDA (US Food and Drug Administration); possibly partly due to inadequate trial design since efficacy demonstration requires disease progression in the placebo group. We investigated whether combinations ...
July 24, 2009
Journal:
Arthritis Res Ther
Author:
Dam EB, Loog M, Christiansen C, Byrjalsen I, Folkesson J, Nielsen M, Qazi AA, Pettersen PC, Garnero P, Karsdal MA
RATIONALE AND OBJECTIVES: Cartilage loss as determined by magnetic resonance imaging (MRI) or joint space narrowing as determined by x-ray is the result of cartilage erosion. However, metabolic processes within the cartilage that later result in cartilage loss may be a more sensitive assessment meth...
October 14, 2007
Journal:
Acad Radiol
Author:
Qazi AA, Dam EB, Nielsen M, Karsdal MA, Pettersen PC, Christiansen C
OBJECTIVE: Cartilage loss as determined either by magnetic resonance imaging (MRI) or by joint space narrowing in X-rays is the result of cartilage erosion. However, metabolic processes within the cartilage that later result in cartilage loss may be a more accurate assessment method for early change...
May 10, 2007
Journal:
Osteoarthritis Cartilage
Author:
Qazi AA, Folkesson J, Karsdal MA, Christiansen C, Dam EB
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