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Objective: The specific degradation of type II collagen and aggrecan by matrix metalloproteinase (MMP)-9, -13 and ADAMTS-4 and -5 (aggrecanase-1 and -2) in the cartilage matrix is a critical step in pathology of osteoarthritis (OA). The aims of this study were: i) To investigate the relative contrib...
April 24, 2015
Journal:
PLoS One
Author:
He Y, Zheng Q, Jiang M, Christiansen TG, Kassem M, Karsdal MA, Bay-Jensen AC
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