Abstract OBJECTIVE Fibroblast growth factor (FGF) 18 has been shown to increase cartilage volume when injected intra-articularly in animal models of osteoarthritis (OA) and in patients with knee OA (during clinical development of the recombinant human FGF18, sprifermin). However, the exact nature of this effect is still unknown. In this study, we aimed to investigate […]
Sprifermin (rhFGF18) enables proliferation of chondrocytes producing a hyaline cartilage matrix.
November 1, 2017
Osteoarthritis Cartilage