Abstract BACKGROUND Osteoarthritis is associated with increased bone resorption and increased cartilage degradation in the subchondral bone and joint. The objective of the present study was to determine whether Tibolone, a synthetic steroid with estrogenic, androgenic, and progestogenic properties, would have similar dual actions on both bone and cartilage turnover, as reported previously with some […]
Tibolone inhibits bone resorption without secondary positive effects on cartilage degradation.
November 18, 2008
BMC Musculoskelet Disord