Abstract INTRODUCTION The medical need in the haemophilic (HF) field to reduce bleeding incidents requires measurement of the annual bleeding rate (ABR) in haemophiliacs. Vascular rupture is associated with damage to the vascular endothelium causing exposure of the basement membrane. Endothelial cells and matrix impairment may be associated with joint bleeds and later development of […]
The endothelial specific isoform of type XVIII collagen correlates to annual bleeding rate in haemophilia patients.
January 1, 2018
PLoS One