Abstract BACKGROUND Renal fibrogenesis is associated with increased ECM remodeling and release of collagen fragments in urine in progressive renal disease. We investigated the diagnostic value of urinary collagen degradation products in a proteinuria-driven fibrosis rat model with and without anti-fibrotic S1P-receptor modulator FTY720 treatment. METHODS Proteinuria was induced in male Wistar rats by Adriamycin […]
Urinary collagen degradation products as early markers of progressive renal fibrosis.
March 20, 2017
J Transl Med