Abstract BACKGROUND Chronic obstructive pulmonary disease (COPD) is characterized by airflow obstruction and loss of lung tissue mainly consisting of extracellular matrix (ECM). Three of the main ECM components are type I collagen, the main constituent in the interstitial matrix, type VI collagen, and elastin, the signature protein of the lungs. During pathological remodeling driven […]
Biomarkers of extracellular matrix turnover are associated with emphysema and eosinophilic-bronchitis in COPD.
January 19, 2017
Respir Res