Abstract Articular cartilage deterioration, which includes cartilage degradation and chondrocyte hypertrophy, is a hallmark of degenerative joint diseases (DJD). Chondrocyte hypertrophy is initiated in the deep layer of the cartilage; thus, a robust explants model for investigation of hypertrophy should include this zone. The aim of this study was to characterize and investigate the hypertrophy-promoting […]
Investigation of chondrocyte hypertrophy and cartilage calcification in a full-depth articular cartilage explants model.
February 1, 2013
Rheumatol Int