That’s where endotrophin, a product of collagen formation, comes into the picture. Endotrophin reflects the activity of key collagen-producing cells: fibroblasts. Endotrophin measured by the nordicPRO-C6™ assay, can identify HFpEF patients with a very aggressive endotype, highly affected by fibrosis.
- NordicPRO-C6™ is a robust prognostic biomarker in HFpEF patients that can identify a population at higher risk.
- Endotrophin can be used for trial enrichment to select a high-risk endotype in clinical studies.
Among all HFpEF endotypes, there is another, unique, patient group – the ones with high fibroblast activity, which can be quantified by nordicPRO-C6™. It doesn’t matter if you’re old, obese, or frail, your nordicPRO-C6™ can still be high.
