Biomarkers

A neo-epitope fragment of type I collagen generated by MMP activity, quantifying pathological soft tissue destruction and extracellular matrix turnover.

A neo-epitope fragment of type II collagen generated by matrix metalloproteinase activity, enabling direct assessment of cartilage degradation and turnover.

A matrix metalloproteinase-generated fragment of type III collagen, reflecting extracellular matrix remodeling and enabling assessment of fibrotic activity.

A neo-epitope fragment of type IV collagen generated by matrix metalloproteinase activity, enabling non-invasive assessment of basement membrane degradation and extracellular matrix remodeling in chronic inflammatory and fibrotic diseases.

A neo-epitope fragment of type III collagen released during extracellular matrix remodeling, enabling non-invasive quantification of active fibrogenesis and dynamic assessment of fibrosis progression and treatment response.

A fragment of C-terminal type VIa3 collagen (Endotrophin), enabling non-invasive quantification of fibrogenesis, tissue remodeling and wound healing across chronic diseases.

A neo-epitope fragment of the α6 chain of type VI collagen, enabling non-invasive monitoring of dermal extracellular matrix remodeling and fibroblast activation in inflammatory skin disorders.

A fragment of type VIa1 collagen released by MMP-2. Special beaded filament collagen measuring interstitial ECM destruction. A neo-epitope fragment of type VI collagen generated by matrix metalloproteinase activity, enabling non-invasive assessment of interstitial extracellular matrix remodeling in fibrotic and oncological conditions.

A neo-epitope fragment of type VII collagen generated by matrix metalloproteinase activity, enabling non-invasive monitoring of dermal-epidermal junction integrity and tissue remodeling in fibrotic and inflammatory skin disorders.

A neo-epitope fragment of elastin generated by neutrophil elastase activity, enabling non-invasive monitoring of extracellular matrix degradation and inflammation in chronic respiratory and gastrointestinal diseases.