Biomarkers

A neo-epitope fragment of type I collagen generated by MMP activity, quantifying pathological soft tissue destruction and extracellular matrix turnover.

A neo-epitope fragment of type II collagen generated by matrix metalloproteinase activity, enabling direct assessment of cartilage degradation and turnover.

A matrix metalloproteinase-generated fragment of type III collagen, reflecting extracellular matrix remodeling and enabling assessment of fibrotic activity.

A granzyme B-generated neo-epitope fragment of type IV collagen, enabling non-invasive assessment of T-cell infiltration and basement membrane remodeling in tumor and inflammatory microenvironments.

A neo-epitope fragment of type IV collagen generated by matrix metalloproteinase activity, enabling non-invasive assessment of basement membrane degradation and extracellular matrix remodeling in chronic inflammatory and fibrotic diseases.

A fragment of S100A9 (calprotectin) released by neutrophil elastase measured in blood, enabling precise assessment of active neutrophil-driven inflammation in systemic and tissue-specific conditions.