PRO-PAR2
A serine protease-mediated fragment generated after cleavage and release from the N-terminal of PAR2, enabling non-invasive monitoring of PAR2 activation and associated inflammatory processes in rheumatic diseases.
Key features and values
- Quantifies N-terminal fragments of PAR2 generated by serine protease activity, reflecting receptor activation.
- Provides a non-invasive measure of PAR2-mediated inflammatory processes.
- Supports monitoring of disease progression and response to therapies targeting PAR2 pathways.
- Applicable in research on rheumatic diseases characterized by PAR2 activation, such as rheumatoid arthritis and osteoarthritis.
- Facilitates evaluation of interventions aimed at modulating PAR2-mediated inflammation.
- Complements other biomarkers for a comprehensive assessment of inflammatory dynamics.
- Utilized in studies investigating the role of PAR2 activation in disease progression and treatment response.
Description
The PRO-PAR2 biomarker assay measures specific fragments generated after serine protease-mediated cleavage and release from the N-terminal of PAR2, serving as an indicator of receptor activation and associated inflammatory processes. This non-invasive assay provides insights into PAR2-mediated inflammation in rheumatic diseases. By quantifying these specific fragments, the PRO-PAR2 assay aids in monitoring disease progression, evaluating treatment efficacy, and understanding the underlying mechanisms of PAR2-related inflammation. It serves as a valuable tool in research settings for assessing the dynamics of inflammatory activity related to PAR2 activation.
Nordic Bioscience’s assays and services are research use only products and services and do not qualify for medical or diagnostic purposes.
