PRO-C5
PopularA fragment of the C-terminal propeptide of type V fibrillar collagen, enabling non-invasive monitoring of extracellular matrix, myfibroblast and cancer-associated fibroblast (CAFs) formation, indicating fibrotic activity in hepatic and oncological conditions.
Key features and values
- Quantifies C-terminal propeptide fragments of type V collagen, reflecting extracellular matrix formation.
- Indicates fibrotic activity associated with hepatic fibrosis and tumor stroma remodeling.
- Provides a non-invasive measure of fibrogenesis in liver diseases and cancer.
- Supports monitoring of disease progression and response to therapies targeting fibrotic processes.
- Applicable in research on conditions characterized by aberrant extracellular matrix turnover, such as cirrhosis and solid tumors.
- Facilitates evaluation of interventions aimed at modulating extracellular matrix formation.
- Complements other biomarkers for a comprehensive assessment of tissue remodeling dynamics.
Description
The PRO-C5 biomarker assay measures specific fragments of the C-terminal propeptide of type V collagen, serving as an indicator of extracellular matrix formation and fibrotic activity. This non-invasive assay provides insights into tissue remodeling processes associated with hepatic fibrosis and tumor stroma remodeling. By quantifying type V collagen formation products, the PRO-C5 assay aids in monitoring disease progression, evaluating treatment efficacy, and understanding the underlying mechanisms of fibrogenesis. It serves as a valuable tool in research settings for assessing the dynamics of extracellular matrix turnover in liver diseases and oncology.
Nordic Bioscience’s assays and services are research use only products and services and do not qualify for medical or diagnostic purposes.
