PRO-C4
A fragment of the 7S domain of type IV collagen, enabling non-invasive monitoring of basement membrane formation and epithelial extracellular matrix remodeling in fibrotic and inflammatory diseases.
Key features and values
- Quantifies 7S domain fragments of type IV collagen associated with basement membrane synthesis.
- Reflects epithelial cell-mediated extracellular matrix formation.
- Provides a non-invasive measure of basement membrane dynamics.
- Supports monitoring of disease progression and response to therapies targeting epithelial remodeling.
- Applicable in research on diseases characterized by aberrant basement membrane turnover, such as liver fibrosis and inflammatory conditions.
- Facilitates evaluation of interventions aimed at modulating basement membrane formation.
- Complements other biomarkers for a comprehensive assessment of extracellular matrix remodeling.
Description
The PRO-C4 biomarker assay measures specific fragments of the 7S domain of type IV collagen, serving as an indicator of basement membrane formation and epithelial extracellular matrix remodeling. This non-invasive assay provides insights into tissue remodeling processes associated with fibrotic and inflammatory diseases. By quantifying type IV collagen formation products, the PRO-C4 assay aids in monitoring disease progression, evaluating treatment efficacy, and understanding the underlying mechanisms of basement membrane dynamics. It serves as a valuable tool in research settings for assessing the dynamics of extracellular matrix turnover.
Nordic Bioscience’s assays and services are research use only products and services and do not qualify for medical or diagnostic purposes.
