PRO-C2 (nordicPRO-C2™)
A fragment of the N-terminal propeptide of type IIB fibrillar collagen, enabling non-invasive monitoring of cartilage formation and chondrocyte anabolic activity in joint diseases such as osteoarthritis.
Key features and values
- Quantifies the N-terminal propeptide of type IIB collagen (PIIBNP), reflecting cartilage formation.
- Provides a non-invasive measure of chondrocyte anabolic activity.
- Differentiates between cartilage formation and degradation processes.
- Supports monitoring of disease progression and response to therapies targeting cartilage repair.
- Applicable in research on joint diseases characterized by cartilage loss, such as osteoarthritis.
- Facilitates evaluation of interventions aimed at enhancing cartilage formation.
- Complements other biomarkers for a comprehensive assessment of cartilage turnover dynamics.
Description
The nordicPRO-C2™ (PRO-C2) biomarker assay measures specific fragments of the N-terminal propeptide of type IIB collagen (PIIBNP), serving as an indicator of cartilage formation and chondrocyte anabolic activity. This non-invasive assay provides insights into cartilage turnover processes associated with joint diseases such as osteoarthritis. By quantifying PIIBNP levels, the PRO-C2 assay aids in monitoring disease progression, evaluating treatment efficacy, and understanding the underlying mechanisms of cartilage repair and degradation. It serves as a valuable tool in research settings for assessing the dynamics of cartilage formation and chondrocyte function.
Nordic Bioscience’s assays and services are research use only products and services and do not qualify for medical or diagnostic purposes.
