EL-NE
A neo-epitope fragment of elastin generated by neutrophil elastase activity, enabling non-invasive monitoring of extracellular matrix degradation and inflammation in chronic respiratory and gastrointestinal diseases.
Key features and values
- Quantifies elastin fragments produced by neutrophil elastase activity.
- Provides a non-invasive measure of extracellular matrix degradation.
- Applicable in research on chronic obstructive pulmonary disease (COPD) and inflammatory bowel disease (IBD).
- Facilitates monitoring of disease activity and therapeutic response.
- Supports evaluation of interventions aimed at modulating inflammatory processes.
- Complements other biomarkers for a comprehensive assessment of tissue remodeling.
- For use in research settings to advance understanding of inflammation-related pathology
Description
The EL-NE biomarker assay quantifies a specific neo-epitope fragment of elastin generated by neutrophil elastase activity. This non-invasive assay serves as an indicator of extracellular matrix degradation and inflammation, providing insights into disease activity in chronic respiratory conditions such as COPD and gastrointestinal disorders like IBD. By measuring EL-NE levels, researchers can monitor disease progression, evaluate therapeutic efficacy, and stratify patients in clinical studies targeting inflammatory pathways. The assay supports a comprehensive understanding of tissue remodeling and its role in chronic diseases.
Nordic Bioscience’s assays and services are research use only products and services and do not qualify for medical or diagnostic purposes.
