Biomarkers

A neo-epitope fragment of type I collagen generated by MMP activity, quantifying pathological soft tissue destruction and extracellular matrix turnover.

A matrix metalloproteinase-generated fragment of type III collagen, reflecting extracellular matrix remodeling and enabling assessment of fibrotic activity.

A granzyme B-generated neo-epitope fragment of type IV collagen, enabling non-invasive assessment of T-cell infiltration and basement membrane remodeling in tumor and inflammatory microenvironments.

A neo-epitope fragment of type IV collagen generated by matrix metalloproteinase activity, enabling non-invasive assessment of basement membrane degradation and extracellular matrix remodeling in chronic inflammatory and fibrotic diseases.

A fragment of the alpha-1 chain of type III collagen generated by human neutrophil elastase (HNE), enabling non-invasive detection of early mucosal inflammation and extracellular matrix remodeling in gastrointestinal disorders.

A neo-epitope fragment of type III collagen generated by cathepsin activity, enabling non-invasive assessment of interstitial matrix degradation and fibrotic remodeling in chronic diseases.

A neo-epitope fragment of type III collagen generated by fibroblast activation protein (FAP) activity, enabling non-invasive assessment of fibroblast-driven extracellular matrix remodeling in fibrotic and oncologic conditions.

A fragment of type VIa1 collagen released by MMP-2. Special beaded filament collagen measuring interstitial ECM destruction. A neo-epitope fragment of type VI collagen generated by matrix metalloproteinase activity, enabling non-invasive assessment of interstitial extracellular matrix remodeling in fibrotic and oncological conditions.

A fragment of nidogen-1 cleaved by cathepsin S, enabling non-invasive monitoring of basement membrane degradation and tumor microenvironment remodeling in cancer.