ELP-3

Neo-epitope of proteinase-3 mediated degradation of elastin. Marker of ECM degradation and neutrophil activation and degranulation.

Key features and values

  • Elastin degradation mediated by protease 3.
  • Measures extracellular matrix degradation via neutrophil serine proteases.
  • Marker of neutrophil activation and degranulation.

Therapeutic area
Gastroenterology, Respiratory diseases

Biomarker panels
Lung Inflammation, Mucosal Damage, Mucosal Damage Resolution

Function
Stromal reactivity, Elastin, Neutrophil activity, ECM degradation