C4Ma3

Neo-epitope of MMP-2,9,12 mediated degradation of type IV collagen alpha 3 chain. Networking forming collagen measuring basement membrane destruction.

Key features and values

  • MMP mediated type IV collagen degradation of the alpha 3 chain.
  • Measures basement membrane destruction.
  • Most abundant protein of the basement membrane.
  • Networking forming collagen.

Therapeutic area
Respiratory diseases, Rheumatology

Biomarker panels
Lung Epithelial Damage & Thrombosis

Function
Basement membrane degradation

Alternative names
C4M12a3