Find an abstract and a link to most of the publications produced by Nordic Bioscience
Background: Extensive extracellular matrix (ECM) remodeling is a hallmark of metastatic pancreatic ductal adenocarcinoma (mPDA). We investigated fragments of collagen types III (C3M, PRO-C3), VI (PRO-C6), and VIII (C8-C), and versican (VCANM) in plasma as biomarkers for predicting progression-free s...
September 27, 2021
Journal:
J Transl Med.
Author:
Wang S, Bager CL, Karsdal MA, Chondros D, Taverna D, Willumsen N
Background: Patients with chronic kidney disease (CKD) are at increased risk of end-stage renal disease (ESRD) and early mortality. The underlying pathophysiological processes are not entirely understood but may include dysregulation of extracellular matrix formation with accelerated systemic and re...
March 20, 2017
Journal:
J Transl Med.
Author:
Hijmans RS, Yazdani S, Navis G, van Goor H, Karsdal MA, Genovese F, van den Born J, Rasmussen DGK
Disease heterogeneity is as major issue in Type II Diabetes Mellitus (T2DM), and this patient inter-variability might not be sufficiently reflected by measurements of glycated haemoglobin (HbA1c).Β-cell dysfunction and β-cell death are initiating factors in development of T2DM. In fact, β-cells are ...
October 30, 2012
Journal:
J Transl Med.
Author:
Andreassen KV, Hjuler ST, Feigh M, Bay-Jensen AC, Zheng Q, Henriksen K, Karsdal MA, Neutzsky-Wulff AV
Background: Titin is a muscle-specific protein found in cardiac and skeletal muscles which is responsible for restoring passive tension. Levels and functioning of titin have been shown to be affected by cardiac damage. Due to the inherent difficulty of measuring titin levels in vivo in a clinical se...
July 6, 2012
Journal:
J Transl Med.
Author:
Vassiliadis E, Rasmussen LM, Byrjalsen I, Larsen DV, Chaturvedi R, Hosbond S, Saabye L, Diederichsen ACP, Genovese F, Duffin KL, Zheng Q, Leeming DJ, Christiansen C, Karsdal MA
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