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Cardiac fibrosis contributes to the development of heart failure in pulmonary hypertension. We aimed to assess the development of fibrosis and the effects of treatment with the anti-fibrotic agent pirfenidone in pressure overload induced right ventricular (RV) failure. Wistar rat weanlings were rand...
April 2, 2019
Journal:
Pulm Circ
Author:
Andersen S, Axelsen JB, Ringgaard S, Nyengaard JR, Holm Nielsen S, Genovese F, Karsdal MA, Hyldebrandt JA, Sørensen CB, de Man FS, Andersen A, Bogaard JH, Nielsen-Kudsk JE
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