Publications
Find an abstract and a link to most of the publications produced by Nordic Bioscience
Find an abstract and a link to most of the publications produced by Nordic Bioscience
Type XI collagen has been associated with tumor fibrosis and aggressiveness in patients with pancreatic ductal adenocarcinoma (PDAC). The propeptide on Type XI collagen is released into the circulation after proteolytic processing at either amino acid 253 or 511. This allows for a noninvasive biomar...
July 1, 2021
Journal:
Int J Cancer
Author:
Nissen NI, Johansen AZ, Chen IM, Karsdal MA, Diab HMH, Jørgensen LN, Sun S, Manon-Jensen T, He Y, Willumsen N, Johansen JS, Kehlet SN, Langholm LL
Pancreatic ductal adenocarcinoma (PDAC) patients have poor prognosis and poor response to treatment. This is largely due to PDAC being associated with a dense and active stroma and tumor fibrosis (desmoplasia). Desmoplasia is characterized by excessive degradation and formation of the extracellular ...
December 24, 2019
Journal:
Sci Rep
Author:
Willumsen N, Ali SM, Leitzel K, Drabick JJ, Yee N, Polimera HV, Nagabhairu V, Krecko L, Ali A, Maddukuri A, Moku P, Poullose J, Menon H, Pancholy N, Costa L, Karsdal MA, Lipton A
Hyaluronan (HA) and collagen are highly expressed in pancreatic cancer (PC) stroma. HA and collagen accumulation increase tumor interstitial fluid pressure, compromising blood flow and drug penetration. The aim of this biomarker study was to determine the clinical utility of serum HA and the propept...
October 23, 2019
Journal:
Int J Cancer
Author:
Chem IM, Willumsen N, Dehlendorff C, Johansen AZ, Jensen BV, Hansen CP, Hasselby JP, Bojesen SE, Pfeiffer P, Holländer NH, Yilmaz Mk, Karsdal MA, Johansen JS, Nielsen SE
Background: Pancreatic cancer (PC) is an aggressive disease with an urgent need for biomarkers. Hallmarks of PC include increased collagen deposition (desmoplasia) and increased matrix metalloproteinase (MMP) activity. The aim of this study was to investigate whether protein fingerprints of specific...
November 21, 2013
Journal:
BMC Cancer
Author:
Willumsen N, Bager CL, Leeming DJ, Smith V, Karsdal MA, Dornan D, Bay-Jensen AC
Search and find publications that we have published.
Please don't hesitate to contact us if you have any questions or other inquiries.
