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Abstract Abdominal aortic aneurysm (AAA) is a complex disease which is incompletely accounted for. Basement membrane (BM) Collagen IV (COL4A1/A2) is abundant in the artery wall, and several lines of evidence indicate a protective role of baseline COL4A1/A2 in AAA development. Using Col4a1/a2 hemi...
June 18, 2021
Journal:
Sci Rep
Author:
L B Steffensen, J Stubbe, J S Lindholt, H C Beck, M Overgaard, M Bloksgaard, F Genovese, Holm Nielsen S, M L T Tha, M K T Hong Lin, J H Larsen, D R Hansen, G T Jones, M J Bown, Karsdal MA, Rasmussen LM
Angina and no obstructive coronary artery disease (CAD) have an unfavorable prognosis, possibly due to diffuse myocardial fibrosis (DMF). In DMF the proteoglycans biglycan and versican are actively remodeled by matrix metalloproteinase. We investigated biglycan and versican in females with angina an...
March 1, 2021
Journal:
J Cardiovasc Transl Res
Author:
Mygind ND, Holm Nielsen S, Michelsen MM, Pena A, Bechsgaard DF, Suhrs E, Bove KB, F Genovese, Nielsen HB, Karsdal MA, Vejlstrup N, Prescott E, Kastrup J
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