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The Arguello model of cancer metastasis to bone has been used extensively to study breast cancer-induced osteolytic disease. The effects of therapy on skeletal disease and on tumour burden in soft organs are traditionally measured using radiography and/or time-consuming histomorphometry, respectivel...
January 21, 2004
Journal:
Clin Exp Metastasis
Author:
Amhlaoibh RN, Hoegh-Andersen P, Brünner N, Sørensen A, Winding B, Holst-Hansen C, Karsdal MA, Engsig MT, Delaissé JM, Heegaard AM
Bone resorption is critical for the development and the maintenance of the skeleton, and improper regulation of bone resorption leads to pathological situations. Proteinases are necessary for this process. In this review, we show that this need of proteinases is not only because they are required fo...
February 15, 2000
Journal:
Clin Chim Acta
Author:
Delaissé JM, Engsig MT, Everts V, del Carmen Ovejero M, Ferreras M, Lund L, Vu TH, Werb Z, Winding B, Lochter A, Karsdal MA, Troen T, Kirkegaard T, Lenhard T, Heegaard AM, Neff L, Baron R, Foged NT
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