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Osteogenesis imperfecta (OI) is a rare disorder of connective tissue caused by abnormalities in the synthesis or processing of type I collagen. Type I collagen is the most abundant type of collagen and is expressed in almost all connective tissues. Given that type I collagen interacts with other col...
October 2, 2018
Journal:
Bone
Author:
Nicol L, Morar P, Wang Y, Henriksen K, Sun S, Karsdal MA, Smith R, Nagamani SCS, Shapiro J, Lee B, Orwoll E
Purpose: In this study we sought to determine whether a Titin peptide fragment can serve as a clinical biomarker for changes in muscle mass. Methods: Mass spectrometry was used to identify Titin fragment in urine. An antibody against this Titin sequence was raised and used to develop a competitive ...
October 9, 2014
Journal:
Exp Gerontol
Author:
Sun S, Henriksen K, Armbrecht G, Belavý DL, Felsenberg D, Rittweger J, Wang Y, Zheng Q, Nedergaard AF, Karsdal MA
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