INTRODUCTION: The medical need in the haemophilic (HF) field to reduce bleeding incidents requires measurement of the annual bleeding rate (ABR) in haemophiliacs. Vascular rupture is associated with damage to the vascular endothelium causing exposure of the basement membrane. Endothelial cells and m...

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January 10, 2018

PLoS One

Kjeld NG, Karsdal MA, Sun S, Manon-Jensen T, Hua BL

Collagens mediate essential hemostasis by maintaining the integrity and stability of the vascular wall. Imbalanced turnover of collagens by uncontrolled formation and/or degradation may result in pathologic conditions such as fibrosis. Thickening of the vessel wall because of accumulation of collage...

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March 14, 2016

J Thromb Haemost

Manon-Jensen T, Kjeld NG, Karsdal MA

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