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CONTEXT AND OBJECTIVE: We evaluated the predictive value of serum cartilage oligomeric matrix protein (sCOMP) levels over 20 years on the development of radiographic (RKOA) and painful knee osteoarthritis (KOA) in a longitudinal cohort of middle-aged women. MATERIALS AND METHODS: Five hundred and n...
December 21, 2015
Journal:
Biomarkers
Author:
Kluzek S, Bay-Jensen AC, Judge A, Karsdal MA, Shorthose M, Hart D, Newton JL, Arden NK, Spector TD
Objective: To evaluate the role of three cartilage-derived biomarkers on osteoarthritis (OA): urinary C-terminal telopeptide (uCTX-II), serum cartilage oligomeric protein (sCOMP), and serum MMP degraded type II collagen (sC2M). Subjects and methods: Samples from 3582 individuals from the Rotterdam ...
May 22, 2014
Journal:
Osteoarthritis Cartilage
Author:
Meulenbelt I, Chassaing E, Arden NK, Bierma-Zeinstra SM, Hart D, Hofman A, Karsdal MA, Kloppenburg M, Kroon HM, Slagboom PE, Spector TD, Uitterlinden AG, van Meurs JB, Bay-Jensen AC, Valdes AM
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