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OBJECTIVES: Type VIII collagen is involved in angiogenesis and remodeling of arteries. We hypothesized that type VIII collagen was upregulated in diseases associated with vascular remodeling, e.g. pulmonary fibrosis and cancer. In this paper we present the development and validation of a competitive...
August 1, 2016
Journal:
Clin Biochem
Author:
Hansen NU, Willumsen N, Larsen L, Karsdal MA, Leeming DJ, Bülow Sand JM
Background: The aim of this study was to develop and validate a model for pulmonary fibrosis, using ex vivo tissue cultures of lungs from bleomycin treated animals, enabling the investigation of fibrosis remodeling using novel biomarkers for the detection of ECM protein fragments. The combination of...
July 5, 2016
Journal:
Respir Res.
Author:
Hansen NU, Karsdal MA, Brockbank S, Cruwys S, Rønnow S, Christiansen C
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