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Having previously shown that levels of the citrullinated vimentin peptide VICM are raised in liver fibrosis in rats, we aimed to investigate whether inhibition of citrullination as measured by VICM levels could affect fibrogenesis.\r\n\r\nMETHODS:\r\nFibrogenesis was evaluated by quantitative histol...
May 14, 2013
Journal:
Am J Transl Res
Author:
Vassiliadis E, Veidal SS, Kristiansen MN, Hansen C, Jorgensen M, Leeming DJ, Karsdal MA
AIM:To measure levels of the collagen V formation marker CO5-1230 during liver fibrosis progression and regression.METHODS:Monoclonal antibodies were raised against the sequence TAALGDIMGH located at the start of the C-terminal propeptide between amino acid position 1230 and 1239 (CO5-1230). An assa...
June 7, 2012
Journal:
Biomarker Insights
Author:
Vassiliadis E, Veidal SS, Hansen C, Karsdal MA, Leeming DJ
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