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INTRODUCTION: At present, no disease-modifying osteoarthritis drugs (DMOADS) are approved by the FDA (US Food and Drug Administration); possibly partly due to inadequate trial design since efficacy demonstration requires disease progression in the placebo group. We investigated whether combinations ...
July 24, 2009
Journal:
Arthritis Res Ther
Author:
Dam EB, Loog M, Christiansen C, Byrjalsen I, Folkesson J, Nielsen M, Qazi AA, Pettersen PC, Garnero P, Karsdal MA
The objective of this study was to quantitatively assess the surface curvature of the articular cartilage from low-field magnetic resonance imaging (MRI) data, and to investigate its role in populations with varying radiographic signs of osteoarthritis (OA), cross-sectionally and longitudinally. The...
June 6, 2008
Journal:
Magn Reson Med
Author:
Folkesson J, Dam EB, Olsen OF, Karsdal MA, Pettersen PC, Christiansen C
OBJECTIVE: Cartilage loss as determined either by magnetic resonance imaging (MRI) or by joint space narrowing in X-rays is the result of cartilage erosion. However, metabolic processes within the cartilage that later result in cartilage loss may be a more accurate assessment method for early change...
May 10, 2007
Journal:
Osteoarthritis Cartilage
Author:
Qazi AA, Folkesson J, Karsdal MA, Christiansen C, Dam EB
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